Rashid H, Ezedum S, Morley A R, Kerr D N
Br Med J. 1980 Aug 2;281(6236):347-50. doi: 10.1136/bmj.281.6236.347.
Seven patients with slight but definite proliferative changes in the glomeruli achieved complete remission of the nephrotic syndrome when treated with prednisone. The patterns of response and, in three cases, repeated relapse and response suggested that this was more than a coincidental spontaneous cure. A controlled trial of corticosteroids in patients with slight proliferative glomerulonephritis and severe nephrotic syndrome should be carried out to verify these results.
7例肾小球有轻微但明确增殖性改变的患者在接受泼尼松治疗后，肾病综合征完全缓解。缓解模式以及3例患者的反复复发和缓解提示，这并非偶然的自发治愈。应对轻度增殖性肾小球肾炎伴严重肾病综合征患者进行皮质类固醇对照试验，以验证这些结果。
