Gordon C J, Heath J E
Brain Res Bull. 1980 Sep-Oct;5(5):515-8. doi: 10.1016/0361-9230(80)90256-7.
Recent data have shown the presence of some hypothalamic neurons with a slow bursting activity. This study reports the interactions of slow bursting neurons with thermoregulatory control in the preoptic/anterior hypothalamus (POAH). Ninety-seven single units studied with direct thermal stimulation and with central injections of norepinephrine (NE) or serotonin (5-HT) were assessed for slow bursting activity. Twenty-one percent of the neurons had slow bursting activity patterns with frequencies ranging from 0.02-0.10 Hz. Intraventricular or direct POAH injected monoamines frequently inhibited bursting activity during normothermia and/or POAH thermal stimulation. Slow bursting neurons may elicit rhythmic thermoregulatory motor outputs, neurosecretion, and infraslow DC potentials in the central nervous system.
近期数据显示存在一些具有缓慢爆发性活动的下丘脑神经元。本研究报告了前脑内侧区/下丘脑前部（POAH）中缓慢爆发性神经元与体温调节控制之间的相互作用。对通过直接热刺激以及脑室内注射去甲肾上腺素（NE）或血清素（5-HT）进行研究的97个单神经元的缓慢爆发性活动进行了评估。21%的神经元具有缓慢爆发性活动模式，频率范围为0.02 - 0.10赫兹。在体温正常和/或POAH热刺激期间，脑室内或直接注入POAH的单胺类物质常常会抑制爆发性活动。缓慢爆发性神经元可能会引发中枢神经系统中有节奏的体温调节运动输出、神经分泌以及超慢直流电位。
