按推荐剂量口服给药及停药后猪可食用组织中磺胺二甲嘧啶的残留情况。
Sulfamethazine residues in uncooked edible tissues of port following recommended oral administration and withdrawal.
作者信息
Saschenbrecker P W, Fish N A
出版信息
Can J Comp Med. 1980 Jul;44(3):338-45.
Commercial feed rations containing sulfamethazine at the level of 110 ppm were fed for a period of 65 days to market pigs in a study simulating normal farm practices. The levels of sulfamethazine at the end of medication were in excess of 10 ppm in liver and kidney and up to 2.6 ppm in muscle tissues. Concentrations of sulfamethazine in tissues from pigs after withdrawal of medicated feed depleted to 0.1 ppm within nine days. The rate of depletion was similar for all tissues. It was observed that storage of tissue samples at freezer temperature (-20 degrees C) for 30 days further reduces sulfamethazine levels by 3 to 20% of their original value.
在一项模拟正常农场做法的研究中，给上市猪喂食了含有110 ppm磺胺二甲嘧啶的商业饲料配方，持续65天。用药结束时，肝脏和肾脏中磺胺二甲嘧啶的含量超过10 ppm，肌肉组织中高达2.6 ppm。停用加药饲料后，猪组织中磺胺二甲嘧啶的浓度在九天内降至0.1 ppm。所有组织的消耗速率相似。观察到在冷冻温度（-20摄氏度）下将组织样本储存30天，可使磺胺二甲嘧啶水平进一步降低其原始值的3%至20%。
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