Gupta N, Cohen J L, Rosenbaum C, Raam S
Cancer. 1980 Oct 15;46(8):1781-4. doi: 10.1002/1097-0142(19801015)46:8<1781::aid-cncr2820460814>3.0.co;2-f.
Estrogen receptor assays were performed on tumor specimens from 6 male patients with documented breast cancer. Five out of six (83%) males had positive ER assays with values ranging from 23-384 femtomoles per mg cytosol protein. A review of the literature showed that 32 out of 38 patients (84%) reported were positive for estrogen receptor. Four out of five ER positive males responded to orchiectomy. Estrogen receptors are present in a high percentage of males with breast cancer and may predict response to treatment, similar to female breast cancer.
对6名确诊为乳腺癌的男性患者的肿瘤标本进行了雌激素受体检测。6名男性中有5名（83%）雌激素受体检测呈阳性，其值范围为每毫克胞浆蛋白23 - 384飞摩尔。文献综述显示，所报道的38例患者中有32例（84%）雌激素受体呈阳性。5名雌激素受体阳性的男性中有4名对睾丸切除术有反应。雌激素受体在高比例的男性乳腺癌患者中存在，并且可能预测对治疗的反应，这与女性乳腺癌相似。
