Chan C W, Hoaglund F T
Clin Orthop Relat Res. 1980 Jul-Aug(150):253-60.
In 3,876 autopsies performed between 1964 and 1974 in adult Hong Kong Chinese, the incidence of pulmonary thromboembolism was 0.75%. In a prospective study of 70 autopsies, the right lungs were inflated, fixed, slab-sectioned, and studied for pulmonary thromboembolism. Twenty-seven per cent had evidence of pulmonary thromboembolism, although in only one case was the lesion the cause of death. In another 62 autopsies, routine dissection of pelvic and both lower extremity veins revealed that 18% had evidence of thrombosis. Eighty-three per cent of these had pulmonary thromboembolism; in 3 of these 62 cases (5%) pulmonary thromboembolism was the cause of death. Massive pulmonary thromboembolism in the Hong Kong Chinese is much less frequent than in Caucasians. The finding of many small asymptomatic pulmonary thromboemboli in both racial groups suggests that pulmonary circulation performs a physiologic filtering function. The rarity of massive clots in the Chinese warrants further investigation and special attention to biomechanics of thrombosis formation and detachment.
在1964年至1974年间对成年香港华人进行的3876例尸检中,肺血栓栓塞的发生率为0.75%。在一项对70例尸检的前瞻性研究中,右肺被充气、固定、制成切片,并进行肺血栓栓塞研究。27%的病例有肺血栓栓塞的证据,尽管只有1例病变是死亡原因。在另外62例尸检中,对盆腔和双下肢静脉进行常规解剖发现,18%有血栓形成的证据。其中83%有肺血栓栓塞;在这62例病例中有3例(5%)肺血栓栓塞是死亡原因。香港华人中大面积肺血栓栓塞的发生率远低于高加索人。在两个种族群体中均发现许多小的无症状肺血栓栓子,这表明肺循环具有生理过滤功能。华人中罕见大面积血栓,这值得进一步研究,并特别关注血栓形成和脱落的生物力学。