Ryhänen P, Helkala E L, Ihalainen O, Hollmén A, Rantakylä S, Merilä M, TUohino V, Pietarila M, Horttonen L
Ann Clin Res. 1978 Dec;10(6):318-22.
The psychological effects of halothane, methoxyflurane, combined analgesic-relaxant anaesthesia, and epidural anaesthesia were assessed before one, and seven days after anaesthesia in 72 patients having operations for varicose veins. Subjective anxiety evaluation (Hamilton Anxiety Rating Scale) and personality tests of self-appraisal (Minnesota Multiphasic Personality Inventory) as well as of superficial (Wartegg's test) and profound (Rorschach's test) projection showed no significant differences among these methods of anaesthesia. Performance tests measuring memory for designs (modified Graham-Kendall memory for designs), short-term memory (digit span of Wechsler Adult Intelligence Scale), learning (nonsense word series), perception (symmetry-drawing), speed of observation (Bourdon-Wiersma) and visualization also revealed no significant psychological changes compared to the control (epidural anaesthesia) group. The methods of anaesthesia used therefore showed no harmful psychological effects and are in this respect safe in clinical use.
对72例接受静脉曲张手术的患者，在麻醉前1天以及麻醉后7天，评估了氟烷、甲氧氟烷、联合镇痛 - 松弛麻醉和硬膜外麻醉的心理效应。主观焦虑评估（汉密尔顿焦虑量表）、自我评估的人格测试（明尼苏达多相人格调查表）以及浅层（瓦泰格测试）和深层（罗夏测试）投射均显示，这些麻醉方法之间无显著差异。测量图案记忆（改良格雷厄姆 - 肯德尔图案记忆）、短期记忆（韦氏成人智力量表数字广度）、学习（无意义单词系列）、感知（对称绘图）、观察速度（布尔东 - 维尔斯马测试）和视觉化的性能测试也显示，与对照组（硬膜外麻醉）相比，无显著的心理变化。因此，所使用的麻醉方法未显示出有害的心理效应，在这方面临床使用是安全的。
