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1
Reduced leucocyte zinc in liver disease.肝病患者白细胞锌含量降低。
Gut. 1980 Jul;21(7):561-4. doi: 10.1136/gut.21.7.561.
2
Relation between zinc status and hepatic functional reserve in patients with liver disease.肝病患者锌状态与肝功能储备之间的关系。
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Screening for Zinc Deficiency in Patients with Cirrhosis: When Should We Start?肝硬化患者锌缺乏的筛查:我们应何时开始?
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3
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Zinc and the liver: an active interaction.锌与肝脏:一种活跃的相互作用。
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本文引用的文献

1
ZINC METABOLISM AND CHRONIC ALCOHOLISM.锌代谢与慢性酒精中毒
Am J Clin Nutr. 1965 Aug;17:57-63. doi: 10.1093/ajcn/17.2.57.
2
Zinc in human blood cells: normal values and abnormalities associated with liver disease.人体血细胞中的锌:正常值及与肝脏疾病相关的异常情况。
J Clin Invest. 1960 Nov;39(11):1651-6. doi: 10.1172/JCI104188.
3
Zinc metabolism in hepatic dysfunction. II. Correlation of metabolic patterns with biochemical findings.肝功能不全时的锌代谢。II. 代谢模式与生化检查结果的相关性。
N Engl J Med. 1957 Nov 28;257(22):1055-65. doi: 10.1056/NEJM195711282572201.
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Determination of zinc in biological fluids by atomic absorption spectrophotometry in normal and cirrhotic subjects.
J Lab Clin Med. 1965 Sep;66(3):508-16.
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Intracellular concentrations of water and of the principal electrolytes determined by analysis of isolated human leucocytes.
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6
Zinc and collagen content of cirrhotic liver.
Am J Dig Dis. 1970 Sep;15(9):797-802. doi: 10.1007/BF02236039.
7
Binding of zinc to amino acids and serum proteins in vitro.锌在体外与氨基酸及血清蛋白的结合
J Lab Clin Med. 1970 Sep;76(3):416-25.
8
The role of zinc in bone metabolism.
Clin Orthop Relat Res. 1974(103):212-34. doi: 10.1097/00003086-197409000-00084.
9
Experimental zinc deficiency in humans.
Ann Intern Med. 1978 Oct;89(4):483-90. doi: 10.7326/0003-4819-89-4-483.
10
Changes in the electrolyte content of leucocytes at different clinical stages of cirrhosis.肝硬化不同临床阶段白细胞电解质含量的变化
Gut. 1978 Jul;19(7):650-4. doi: 10.1136/gut.19.7.650.

肝病患者白细胞锌含量降低。

Reduced leucocyte zinc in liver disease.

作者信息

Keeling P W, Jones R B, Hilton P J, Thompson R P

出版信息

Gut. 1980 Jul;21(7):561-4. doi: 10.1136/gut.21.7.561.

DOI:10.1136/gut.21.7.561
PMID:7429319
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1419894/
Abstract

The zinc content of peripheral blood leucocytes has been measured in normal controls and in three groups of patients with liver disease. A significant reduction in leucocyte zinc, but not erythrocyte zinc, was observed in patients with primary biliary cirrhosis, alcoholic cirrhosis, and active chronic hepatitis. It is suggested that the nucleated tissues of some patients with liver disease are therefore zinc deficient, and that leucocyte zinc may prove of value in the assessment of the zinc status of such patients.

摘要

已对正常对照组以及三组肝病患者外周血白细胞的锌含量进行了测定。在原发性胆汁性肝硬化、酒精性肝硬化和活动性慢性肝炎患者中,观察到白细胞锌含量显著降低,但红细胞锌含量未降低。因此表明,一些肝病患者的有核组织存在锌缺乏,并且白细胞锌可能在评估此类患者的锌状态方面具有价值。