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酒精性胰腺炎和慢性肝病患者红细胞及唾液中的血型Lewis表型

Blood group lewis phenotype on erythrocytes and in saliva in alcoholic pancreatitis and chronic liver disease.

作者信息

Stigendal L, Olsson R, Rydberg L, Samuelsson B E

出版信息

J Clin Pathol. 1984 Jul;37(7):778-82. doi: 10.1136/jcp.37.7.778.

DOI:10.1136/jcp.37.7.778
PMID:6430969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC498808/
Abstract

The distributions of ABO, rhesus, and Lewis blood group antigens were studied in patients with alcoholic cirrhosis, alcoholic pancreatitis, chronic active hepatitis, and primary biliary cirrhosis. There were no differences in frequencies of ABO and rhesus blood group antigens between the groups or in comparison with a control group of blood donors. Lewis phenotype Le (a- b-), however, was more common on erythrocytes than in saliva in patients with alcoholic cirrhosis, alcoholic pancreatitis, and severe renal disease but equally common in saliva and on red blood cells in patients with non-alcoholic liver disease. It is suggested that Lewis typing should be performed on saliva because blood typing may give misleading results in some patients.

摘要

对酒精性肝硬化、酒精性胰腺炎、慢性活动性肝炎和原发性胆汁性肝硬化患者的ABO、恒河猴和Lewis血型抗原分布进行了研究。这些组之间以及与献血者对照组相比,ABO和恒河猴血型抗原的频率没有差异。然而,在酒精性肝硬化、酒精性胰腺炎和严重肾病患者中,Lewis表型Le(a - b -)在红细胞上比在唾液中更常见,但在非酒精性肝病患者中,其在唾液和红细胞上同样常见。建议对唾液进行Lewis分型,因为血型检测可能会在一些患者中给出误导性结果。

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Blood group lewis phenotype on erythrocytes and in saliva in alcoholic pancreatitis and chronic liver disease.酒精性胰腺炎和慢性肝病患者红细胞及唾液中的血型Lewis表型
J Clin Pathol. 1984 Jul;37(7):778-82. doi: 10.1136/jcp.37.7.778.
2
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3
[Lewis antigen and diabetes].[刘易斯抗原与糖尿病]
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[Blood group, alcoholism and liver damage (author's transl)].
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引用本文的文献

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The Lewis histo-blood group system: molecular analysis of the 59T>G, 508G>A, and 1067T>A polymorphisms in an Amazonian population.刘易斯组织血型系统:对亚马逊人群中 59T>G、508G>A 和 1067T>A 多态性的分子分析。
PLoS One. 2013 Jul 29;8(7):e69908. doi: 10.1371/journal.pone.0069908. Print 2013.
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Adv Nutr. 2012 May 1;3(3):440S-9S. doi: 10.3945/an.111.001446.
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[Clinical value of the CA 19-9 tumor marker with special reference to the Lewis phenotype].[CA 19-9肿瘤标志物的临床价值,特别提及Lewis血型表型]
Med Klin (Munich). 1997 Apr 15;92(4):228-32. doi: 10.1007/BF03043263.
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The Lewis blood group system in liver transplantation.肝脏移植中的Lewis血型系统。
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Elevated serum levels of Dupan-2 in pancreatic cancer patients negative for Lewis blood group phenotype.Lewis血型表型阴性的胰腺癌患者血清中Dupan-2水平升高。
Br J Cancer. 1991 Nov;64(5):899-902. doi: 10.1038/bjc.1991.422.
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Alpha 1 antitrypsin phenotypes and alcoholic pancreatitis.α1抗胰蛋白酶表型与酒精性胰腺炎
Gut. 1991 Aug;32(8):945-8. doi: 10.1136/gut.32.8.945.

本文引用的文献

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Glycosphingolipids with Lewis blood group activity: uptake by human erythrocytes.具有Lewis血型活性的糖鞘脂:人红细胞的摄取
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Acute pancreatitis with hyperlipemia. Evidence for a persistent defect in lipid metabolism.伴有高脂血症的急性胰腺炎。脂质代谢持续缺陷的证据。
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