Fielding L T, Murphy R J, Reagan M W, Peterson T L
Hosp Community Psychiatry. 1980 Nov;31(11):771-3. doi: 10.1176/ps.31.11.771.
Growing concern over possible institutional drug abuse has made it extremely important to identify procedures to systematically evaluate the therapeutic effectiveness of drugs. The authors describe a two-phase drug assessment program that has permitted an intermediate care facility for the mentally retarded to reduce its reliance on psychoactive medication and to meet the mandates of accreditation and law. The first phase identified individuals who could effectively participate in treatment without medication. The second phase identified minimum effective dosages for those whose maladaptive behavior could not be controlled when medication was abruptly removed. Therapeutic benefits resulting from this individualized drug reduction program are discussed, as are the economic and programmatic benefits to the institution.
对可能存在的机构性药物滥用问题的日益关注,使得确定系统评估药物治疗效果的程序变得极为重要。作者描述了一个两阶段药物评估项目,该项目使得一家为智障人士提供中级护理的机构能够减少对精神活性药物的依赖,并符合认证和法律要求。第一阶段确定了那些无需药物就能有效参与治疗的个体。第二阶段则确定了对于那些在突然停药时适应不良行为无法得到控制的人而言的最低有效剂量。文中讨论了这个个性化药物减量项目所带来的治疗益处,以及该机构所获得的经济和项目效益。