Mills S E, Fechner R E
Hum Pathol. 1980 Sep;11(5 Suppl):583-5.
A 41 year old woman was treated for metrorrhagia with Ovral three times daily for one week, followed by a single daily dose for one month. Hysterectomy and bilateral salpingo-oophorectomy were performed. Histologically the mucosa of both fallopian tubes had large areas of decidual reaction underlying atrophic epithelium. This epithelial stromal dissociation is identical to that seen in the endometria of women taking contraceptive hormones orally, and the hormones are thought to be the cause of the changes in the tubes. These alterations have not been previously described in the salpinx.
一名41岁女性因子宫出血接受治疗,每天服用三次复方炔诺酮片,持续一周,之后每天服用一次,持续一个月。随后进行了子宫切除术和双侧输卵管卵巢切除术。组织学检查显示,双侧输卵管黏膜在萎缩的上皮下方有大片蜕膜反应。这种上皮-间质分离与口服避孕药的女性子宫内膜中所见的情况相同,激素被认为是输卵管变化的原因。这些改变此前在输卵管中尚未有过描述。