2-脱氧链霉胺生物合成中间体的结构解析
Structure elucidation of an intermediate of 2-deoxystreptamine biosynthesis.
作者信息
Igarashi K, Honma T, Fujiwara T, Kondo E
出版信息
J Antibiot (Tokyo). 1980 Aug;33(8):830-5. doi: 10.7164/antibiotics.33.830.
PMID:7429986
Abstract
The structure of a 2-deoxystreptamine (DOS) precursor named S-11-P, which was isolated by using a DOS negative mutant derived from a xylostasin-producing strain of Bacillus circulans B15M, has been elucidated as (1 L)-1,3,5/2,4,-5-aminocyclohexanetetrol by comparison with an authentic specimen, which was synthesized from kanamycin A.
摘要
利用来源于环状芽孢杆菌B15M木糖抑素产生菌的去氧链霉胺（DOS）阴性突变体分离得到的一种名为S-11-P的2-去氧链霉胺（DOS）前体的结构，通过与由卡那霉素A合成的标准样品进行比较，已阐明为(1L)-1,3,5/2,4,-5-氨基环己烷四醇。
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