Hill F W, Sullivan N D
Aust Vet J. 1978 Sep;54(9):447-9. doi: 10.1111/j.1751-0813.1978.tb05577.x.
A 2-year-old male Boxer dog had passed loose faeces mixed with fresh blood and mucus for 8 months. Tenesmus after defaecation was a feature. Colitis was diagnosed from the proctoscopic appearance of the recto-colonic mucosa and confirmed from a biopsy. The disorder proved unresponsive to sulphasalazine therapy, but oral chloramphenicol, betamethasone and prednisolone enemas administered over a 6-week period produced a satisfactory clinical improvement, which persisted for a further 3 weeks without treatment. However, follow-up proctoscopy showed only a marginal improvement in the appearance of the mucosa and appeared to exacerbate further bloody diarrhoea, which persisted. The dog was destroyed and histiocytic ulcerative colitis confirmed at autopsy.
一只2岁的雄性拳师犬排混有鲜血和黏液的稀便达8个月之久。排便后里急后重是其特征。根据直肠结肠黏膜的直肠镜检查结果诊断为结肠炎，并经活检确诊。事实证明该病症对柳氮磺胺吡啶治疗无反应，但在6周内给予口服氯霉素、倍他米松和泼尼松龙灌肠剂后，临床症状有了令人满意的改善，且在未治疗的情况下又持续了3周。然而，后续的直肠镜检查显示黏膜外观仅略有改善，且似乎加剧了持续存在的血性腹泻。这只狗被安乐死，尸检证实为组织细胞性溃疡性结肠炎。
