Tanaka Hiroshi, Nakayama Masanari, Takase Katsuaki
Nakayama Veterinary Hospital, Nara, Japan.
J Vet Med Sci. 2003 Mar;65(3):431-3. doi: 10.1292/jvms.65.431.
A 9-month-old French bulldog was referred for signs of chronic large bowel diarrhea. The dog had an increased frequency of defecation, tenesmus and hematochezia. Flexible colonoscopy showed hyperemia, irregularities and ulcerations with multifocal hemorrhages in the mucosa from the descending colon to the proximal rectum. Multiple colonic biopsies were characterized by infiltrations of PAS positive histiocytes in the lamina propria. A diagnosis of histiocytic ulcerative colitis (HUC) was made, and the animal showed only minimal improvement, although it was treated with nutritional and medical therapies. This is the second case of HUC in French bulldog, a breed which has ancestral relations to Boxer dogs.
一只9个月大的法国斗牛犬因慢性大肠腹泻症状前来就诊。该犬排便频率增加、有里急后重和便血症状。柔性结肠镜检查显示，从降结肠到直肠近端的黏膜有充血、不规则病变及溃疡，并伴有多处出血。多次结肠活检的特征是固有层中有PAS阳性组织细胞浸润。诊断为组织细胞性溃疡性结肠炎（HUC），尽管对该动物进行了营养和药物治疗，但它仅略有改善。这是法国斗牛犬中第二例HUC病例，该品种与拳师犬有亲缘关系。
