Lindberg R, Segall T
Nord Vet Med. 1977 Dec;29(12):552-5.
A case of canine histiocytic ulcerative colitis, a disease of boxers, is here described. It appears that this disease has not been previously reported in Scandinavia. The diagnosis was established at necropsy of a 5-month-old boxer, which had shown bloody diarrhoea since the age of four weeks. Treatment with antibiotics had only given a temporary remission of the condition. Macroscopical findings included thickening of the wall of the descending colon and rectum, multiple ulcers in the rectocolonic mucosa and marked enlargement of the colonic lymph nodes. Microscopically the lesions were characterized by large accumulations of PAS-positive histiocytes, mixed with cells of the plasma cell type, in the mucosa and submucosa of the rectum and descending colon and in the colonic lymph nodes. The importance of using proctocolonoscopy and colon biopsy for the clinical diagnosis of this condition is stressed.
本文描述了一例犬组织细胞性溃疡性结肠炎病例，该病常见于拳师犬。此前斯堪的纳维亚半岛似乎尚未报道过这种疾病。诊断是在对一只5个月大的拳师犬进行尸检时确定的，这只犬自4周龄起就出现了血便。使用抗生素治疗仅使病情得到暂时缓解。宏观检查结果包括降结肠和直肠壁增厚、直肠结肠黏膜多处溃疡以及结肠淋巴结明显肿大。显微镜下，病变特征为直肠和降结肠黏膜及黏膜下层以及结肠淋巴结中有大量PAS阳性组织细胞聚集，并混有浆细胞类型的细胞。强调了使用直肠结肠镜检查和结肠活检对该病进行临床诊断的重要性。
