载脂蛋白对内皮结合脂蛋白脂肪酶活性的影响。
Effects of C apoproteins on the activity of endothelium-bound lipoprotein lipase.
作者信息
Lukens T W, Borensztajn J
出版信息
Biochem J. 1978 Dec 1;175(3):1143-6. doi: 10.1042/bj1751143.
Abstract
Rat apoprotein C-II activated the hydrolysis of triacylglycerol in apoprotein-depleted chylomicrons by lipoprotein lipase in vitro and in the perfused rat heart. Apoproteins C-I and C-III-3 inhibited the hydrolysis of the triacylglycerol moiety in intact and apoprotein C-II-re-activated chylomicrons in vitro, but had no effect on the hydrolysis in situ.
摘要
大鼠载脂蛋白C-II在体外和灌注的大鼠心脏中可激活脂蛋白脂肪酶对脱载脂蛋白乳糜微粒中三酰甘油的水解作用。载脂蛋白C-I和C-III-3在体外可抑制完整的以及经载脂蛋白C-II重新激活的乳糜微粒中三酰甘油部分的水解，但对原位水解没有影响。
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