严重丙吡胺中毒的成功救治
Successful management of serious disopyramide poisoning.
作者信息
Holt D W, Helliwell M, O'Keeffe B, Hayler A M, Marshall C B, Cook G
出版信息
Postgrad Med J. 1980 Apr;56(654):256-60. doi: 10.1136/pgmj.56.654.256.
Abstract
A case of deliberate disopyramide overdosage is described. Circulatory collapse was treated by means of a large dose of isoprenaline, and charcoal haemoperfusion was used in an attempt to enhance the elimination of disopyramide. The suitability of this treatment regime is discussed in the light of findings from animal studies and the implications for the management of the disopyramide-poisoned patient are considered.
摘要
本文描述了一例故意过量服用丙吡胺的病例。通过大剂量异丙肾上腺素治疗循环衰竭，并采用活性炭血液灌流以促进丙吡胺的清除。根据动物研究结果讨论了该治疗方案的适用性，并考虑了其对丙吡胺中毒患者管理的意义。
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引用本文的文献
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Higher efficacy of direct hemoperfusion using coated activated-charcoal column for disopyramide poisoning: A case report.使用包被活性炭柱直接血液灌流治疗丙吡胺中毒的更高疗效：病例报告
Medicine (Baltimore). 2017 Dec;96(49):e8755. doi: 10.1097/MD.0000000000008755.
2
Poisoning due to class IA antiarrhythmic drugs. Quinidine, procainamide and disopyramide.IA类抗心律失常药物中毒。奎尼丁、普鲁卡因胺和丙吡胺。
Drug Saf. 1990 Nov-Dec;5(6):393-420. doi: 10.2165/00002018-199005060-00002.
本文引用的文献
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Torsade De Pointes, an atypical ventricular tachycardia.尖端扭转型室性心动过速，一种非典型室性心动过速。
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Cardiac consequences and treatment of disopyramide intoxication: experimental evaluation in dogs.丙吡胺中毒的心脏后果及治疗：犬类实验评估
Cardiovasc Res. 1979 Nov;13(11):630-4. doi: 10.1093/cvr/13.11.630.
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Experimental disopyramide poisoning: treatment by cardiovascular support and with charcoal hemoperfusion.
J Pharmacol Exp Ther. 1979 Dec;211(3):491-5.
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Treatment of disopyramide overdosage.丙吡胺过量的治疗。
Med J Aust. 1979 Mar 24;1(6):234. doi: 10.5694/j.1326-5377.1979.tb117803.x.
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Disopyramide-induced ventricular fibrillation.丙吡胺诱发的心室颤动。
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