Fedorov V K, Shashkina L F, Shul'man V S, Tsarichenko G V
Probl Endokrinol (Mosk). 1980 Sep-Oct;26(5):50-5.
Two equations of the dose-time-effect dependence during repeated intramuscular injections of testosterone esters are presented. The equation coefficients characterizing both properties of the drugs injected and individual features of the organs exposed to their action are interpreted. Moreover, two equations for calculating duration of the mitotic cycle of the test organ cells are given.
本文给出了重复肌肉注射睾酮酯时剂量-时间-效应依赖性的两个方程。对表征所注射药物特性和受其作用的器官个体特征的方程系数进行了解释。此外，还给出了两个用于计算受试器官细胞有丝分裂周期持续时间的方程。
