["乙肝病毒感染中“e”系统的频率及预后价值"]

[Frequency and prognostic value of the "e" system in hepatitis B virus infection].

作者信息

Onesciuc C, Onesciuc I, Jebeleanu L, Serban I, Gorgan V, Cîrstina D, Oprean N, Feticu M

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1980 Jul-Sep;25(3):175-8.

PMID:7433816

Abstract

The frequency and prognostic value of the "e" system was determined in acute and chronic hepatitis patients and in blood donors by immunodiffusion on Abott rheophoresis plates. The incidence of HBe Ag in acute viral hepatitis was 20% at the beginning of the disease; its persistance indicated a prolonged evolution and a tendency to a chronic course. The presence of anti-HBe at the beginning of the acute disease may indicate the onset of a non-B hepatitis in an HBe carrier. In chronic hepatitis the incidence of HBe Ag was 58% and in blood donors only 6%. Anti-HBe was absent in chronic hepatitis and present in 15% of blood donors.

摘要

通过在雅培电泳板上进行免疫扩散，测定了急性和慢性肝炎患者以及献血者中“e”系统的频率和预后价值。急性病毒性肝炎患者在疾病初期HBe Ag的发生率为20%；其持续存在表明病程延长且有慢性化倾向。急性疾病初期抗-HBe的存在可能提示HBe携带者发生了非B型肝炎。慢性肝炎中HBe Ag的发生率为58%，而献血者中仅为6%。慢性肝炎患者中不存在抗-HBe，而15%的献血者中存在抗-HBe。