Jordanoglou J, Tatsis G, Veslemes M, Charalampakis S, Hadjistavrou C
Thorax. 1980 May;35(5):375-8. doi: 10.1136/thx.35.5.375.
The partial effective times of the expiratory spirogram were calculated in 80 normal non-smoking subjects aged from 20 to 69 years and in 30 patients aged from 30 to 58 years with chronic bronchitis. Of these patients, 28 had a normal FEV1/FVC ratio, while the other two had a low ratio. Partial effective times were calculated for 10% segments of the expired FVC from total lung capacity (0% FVC) to residual volume (100% FVC) and became progressively longer after 50% of the FVC had been expired in normal subjects. The elongation to the partial effective times was more pronounced with age. In the patients with simple chronic bronchitis (normal FEV1/FVC ratio) the partial effective times were longer than normal after 50% of the FVC had been expired and after 10% of the FVC had been expired in the two patients with chronic bronchitis and low FEV1/FVC ratio. The partial effective times of the forced expiratory spirogram, especially that at the 80--90% part of the FVC, seem to be very sensitive indices for the early detection of mild airways obstruction.
对80名年龄在20至69岁的正常非吸烟受试者以及30名年龄在30至58岁的慢性支气管炎患者的呼气肺量图的部分有效时间进行了计算。在这些患者中,28人的FEV1/FVC比值正常,另外两人的该比值较低。从肺总量(0% FVC)到残气量(100% FVC)计算了呼出FVC的10%片段的部分有效时间,在正常受试者中,FVC呼出50%后,部分有效时间逐渐延长。随着年龄增长,部分有效时间的延长更为明显。在单纯慢性支气管炎患者(FEV1/FVC比值正常)中,FVC呼出50%后以及在FEV1/FVC比值较低的两名慢性支气管炎患者中,FVC呼出10%后,部分有效时间均长于正常水平。用力呼气肺量图的部分有效时间,尤其是FVC的80%至90%部分的有效时间,似乎是早期检测轻度气道阻塞的非常敏感的指标。