早期肺气肿时的弹性回缩变化
Elastic recoil changes in early emphysema.
作者信息
Silvers G W, Petty T L, Stanford R E
出版信息
Thorax. 1980 Jul;35(7):490-5. doi: 10.1136/thx.35.7.490.
An attempt was made to determine if emphysema and static lung recoil were related in a group of 65 excised human lungs. We studied 23 normal lungs, 24 lungs with an emphysema score of 5 or less, and 18 lungs with an emphysema score greater than 5. A comparison of the percentage of predicted elastic recoil revealed that both emphysema groups were significantly different from normal lungs. In addition, the total lung capacities were significantly different between the three groups. In the group with an emphysema score greater than 5 we found a linear negative correlation between the extent of emphysema and percent of predicted elastic recoil at 90% total lung capacity (r = -0.696, p < 0.01). We found a negative correlation between the percentage of predicted elastic recoil and the lung volume (r = -0.612, p < 0.01). We conclude that a significant loss of elastic recoil and a significant increase in total lung capacity occurs in the early stages of emphysema.
我们尝试在一组65个切除的人肺中确定肺气肿与静态肺回缩是否相关。我们研究了23个正常肺、24个肺气肿评分小于或等于5的肺以及18个肺气肿评分大于5的肺。对预计弹性回缩百分比的比较显示，两个肺气肿组与正常肺均有显著差异。此外，三组之间的肺总量也有显著差异。在肺气肿评分大于5的组中，我们发现在肺总量90%时，肺气肿程度与预计弹性回缩百分比之间呈线性负相关（r = -0.696，p < 0.01）。我们还发现预计弹性回缩百分比与肺容积之间呈负相关（r = -0.612，p < 0.01）。我们得出结论，在肺气肿早期会出现弹性回缩显著丧失以及肺总量显著增加的情况。
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