Holtås S, Almén T, Golman K, Tejler L
Acta Radiol Diagn (Stockh). 1980;21(3):397-400. doi: 10.1177/028418518002100309.
The influence on albuminuria following nephroangiography was investigated after addition of Ca2+ to the non-ionic contrast medium metrizamide (Amipaque) in the rat and after addition of Ca2+ or Ca2+ and Mg2+ to the experimental non-ionic contrast medium C 29 in the dog. When Ca2+ or CA2+ and Mg2+ were added to metrizamide or C29 in concentrations two to three times th plasma level no influence occurred. Higher concentrations of Ca2+ (10-25 mmol/l) in the metrizamide or C29 solutions resulted in increased albuminuria.
在大鼠的非离子型造影剂甲泛葡胺(阿米培克)中添加钙离子,以及在犬的实验性非离子型造影剂C 29中添加钙离子或钙离子与镁离子后,研究了肾血管造影术后对蛋白尿的影响。当以血浆水平的两到三倍浓度向甲泛葡胺或C 29中添加钙离子或钙离子与镁离子时,未产生影响。甲泛葡胺或C 29溶液中较高浓度的钙离子(10 - 25 mmol/L)会导致蛋白尿增加。