Proteinuria following nephroangiography. V. Influence of calcium and magnesium ions in non-ionic contrast media.

The influence on albuminuria following nephroangiography was investigated after addition of Ca2+ to the non-ionic contrast medium metrizamide (Amipaque) in the rat and after addition of Ca2+ or Ca2+ and Mg2+ to the experimental non-ionic contrast medium C 29 in the dog. When Ca2+ or CA2+ and Mg2+ were added to metrizamide or C29 in concentrations two to three times th plasma level no influence occurred. Higher concentrations of Ca2+ (10-25 mmol/l) in the metrizamide or C29 solutions resulted in increased albuminuria.