Burney M I, Ghafoor A, Saleen M, Webb P A, Casals J
Am J Trop Med Hyg. 1980 Sep;29(5):941-7. doi: 10.4269/ajtmh.1980.29.941.
This paper describes the clinical, epidemiological, and laboratory investigations undertaken to isolate and identify the etiological agent of a nosocomial cluster of hemorrhagic fever cases due to Crimean hemorrhagic fever (CHR)-Congo virus. Since this virus is usually transmitted by ticks it was surprising that the index case, in a nomadic shepherd, occurred during the winter season when ticks are relatively inactive. These are the first cases of CHF-Congo virus found in humans in Pakistan. Investigations on other biological properties, particularly strain differences and virulence, are being continued at the Islamabad laboratory.
本文描述了为分离和鉴定由克里米亚出血热-刚果病毒引起的医院内出血热病例聚集性疫情的病原体所开展的临床、流行病学和实验室调查。由于该病毒通常通过蜱虫传播，所以游牧牧民中的首例病例出现在蜱虫相对不活跃的冬季，这一点令人惊讶。这些是在巴基斯坦发现的首例人类感染刚果出血热病毒的病例。伊斯兰堡实验室正在继续对其他生物学特性，特别是毒株差异和毒力进行研究。
