Mullin B R, Montanaro A J, Reid J D, Nishimura R N
Ann Neurol. 1980 Jun;7(6):587-90. doi: 10.1002/ana.410070615.
Multiple sclerosis serum contains a factor or factors capable of releasing sequestered [14C]glucose from liposomes containing GM1, the major ganglioside present in human central nervous system myelin. Although some control sera can also release large quantities of liposomal glucose, multiple sclerosis and control sera differ in the mechanism of this release. Liposomal damage by multiple sclerosis serum does not appear to be complement mediated, but shares certain releasing characteristics of cholera toxin.
多发性硬化症血清中含有一种或多种因子，能够从含有GM1（人类中枢神经系统髓鞘中主要的神经节苷脂）的脂质体中释放被隔离的[14C]葡萄糖。虽然一些对照血清也能释放大量脂质体葡萄糖，但多发性硬化症血清和对照血清在这种释放机制上有所不同。多发性硬化症血清对脂质体的损伤似乎不是由补体介导的，而是具有霍乱毒素的某些释放特性。
