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肝素对通过流式细胞术获得的胃黏膜DNA分布模式的影响。初步报告。

The influence of heparin on DNA-distribution patterns of gastric mucosa as obtained by flow cytometry. Preliminary report.

作者信息

Weiss H, Heinz U, Wildner G P

出版信息

Arch Geschwulstforsch. 1980;50(2):119-24.

PMID:7436696
Abstract

Preliminary results about the influence of Heparin to DNA-distribution patterns of gastric mucosa obtained by flow cytometry are reported. Changes in the configuration of nuclear chromatin, caused by Heparin, are connected with changes in the stainability; thus they are reflected by DNA-distribution patterns. With precaution, some special features in the 4C region of DNA-distribution patterns of gastric mucosa in severe chronic atrophic gastritis and carcinoma are supposed to be attributed to changes in the nuclear chromatin occurring in these diseases.

摘要

本文报道了关于肝素对通过流式细胞术获得的胃黏膜DNA分布模式影响的初步结果。肝素引起的核染色质构型变化与染色性变化相关;因此,它们通过DNA分布模式得以体现。经谨慎观察,重度慢性萎缩性胃炎和胃癌患者胃黏膜DNA分布模式的4C区域中的一些特殊特征,被认为归因于这些疾病中发生的核染色质变化。

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