Hatle L, Brubakk A, Tromsdal A, Angelsen B
Br Heart J. 1978 Feb;40(2):131-40. doi: 10.1136/hrt.40.2.131.
A noninvasive method is described for measuring the pressure drop across the mitral valve in mitral stensois by Doppler ultrasound. A maximum frequency estimator was used to record maximum velocity in the Doppler signal from the mitral jet. Provided the angle between the ultrasound beam and the maximum velocity is close to zero the pressure drop can be calculated directly. Good correlation was found between Doppler measurements and simultaneous pressure recordings during heart catheterisation in 10 patients. No false negative or false positive diagnoses of mitral stenosis were made among 55 patients (35 patients with mitral stenosis and 20 patients with other valve lesions). The measurements were easy to perform in most patients and the method seems well suited both to diagnose and to follow patients with mitral stenosis.
本文描述了一种通过多普勒超声测量二尖瓣狭窄时二尖瓣跨瓣压差的无创方法。使用最大频率估计器记录二尖瓣血流频谱中的最大速度。若超声束与最大血流速度方向夹角接近零，则可直接计算跨瓣压差。对10例患者进行心导管检查时，发现多普勒测量值与同步压力记录之间具有良好的相关性。在55例患者（35例二尖瓣狭窄患者和20例其他瓣膜病变患者）中，未出现二尖瓣狭窄的假阴性或假阳性诊断。大多数患者的测量操作简便，该方法似乎非常适合二尖瓣狭窄患者的诊断和随访。
