Bing R F, Briggs R S, Burden A C, Russell G I, Swales J D, Thurston H
Clin Endocrinol (Oxf). 1980 Oct;13(4):339-42. doi: 10.1111/j.1365-2265.1980.tb03393.x.
Six patients with hypothyroidism and hypertension whose blood pressure fell to normal when treated with thyroxine (172 +/- 7.2/112 +/- 2.1 to 140 +/- 3.2/84+/- 1.6 mmHg, P < 0.001) are described. Plasma renin activity (1.76 +/- 0.63 ng angiotensin I.ml-1.h-1) was low before treatment. Hypertension with low plasma renin is consistent with sodium retention. Hypertension in the hypothyroid patient only requires further evaluation if it persists after adequate treatment with thyroxine.
本文描述了6例甲状腺功能减退合并高血压患者，这些患者在接受甲状腺素治疗后血压恢复正常（从172±7.2/112±2.1 mmHg降至140±3.2/84±1.6 mmHg，P<0.001）。治疗前血浆肾素活性较低（1.76±0.63 ng血管紧张素I·ml⁻¹·h⁻¹）。低血浆肾素性高血压与钠潴留相符。甲状腺功能减退患者的高血压只有在接受充分的甲状腺素治疗后仍持续存在时才需要进一步评估。
