氧烯洛尔、醋丁洛尔和普萘洛尔对甲状腺功能亢进患者甲状腺激素的影响。
The effect of oxprenolol, acebutolol and propranolol on thyroid hormones in hyperthyroid subjects.
作者信息
Jones M K, John R, Jones G R
出版信息
Clin Endocrinol (Oxf). 1980 Oct;13(4):343-7. doi: 10.1111/j.1365-2265.1980.tb03394.x.
Abstract
Serum thyroid hormone levels were measured before and during 10 days treatment with acebutolol (400 mg/day), oxprenolol (160 mg/day) and propranolol (160 mg/day) eighteen hyperthyroid patients. A significant change in thyroid hormone concentrations was seen only in the group treated with propranolol. Propranolol should be used in preference to beta-adrenoreceptor blocking drugs with partial agonist activity, in the treatment of hyperthyroidism.
摘要
对18例甲状腺功能亢进患者在使用醋丁洛尔（400毫克/天）、氧烯洛尔（160毫克/天）和普萘洛尔（160毫克/天）治疗前及治疗10天期间测定血清甲状腺激素水平。仅在使用普萘洛尔治疗的组中观察到甲状腺激素浓度有显著变化。在甲状腺功能亢进的治疗中，应优先使用普萘洛尔而非具有部分激动剂活性的β-肾上腺素受体阻断药。
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