Gillies J D, Seshia S S
Dev Med Child Neurol. 1980 Oct;22(5):642-8. doi: 10.1111/j.1469-8749.1980.tb04378.x.
The data have been analysed for 17 children who showed features of the vegetative state following an acute illness that resulted in coma. 15 were under three years of age. Diffuse anoxia/ischaemia (N=12) and meningitis (N=4) were the most common causes of the comatose state. Seven children died, and nine of the 10 survivors have remained severely neurodevelopmentally handicapped, with no cognitive function (follow-up two months to five years). One child became ambulant a year after the initial insult and is moderately retarded. The findings suggest that children who develop the vegetative state following an illness resulting in coma have a poor prognosis and that decorticate or decerebrate responses, roving eye-movements and spontaneous blinking may be early indicators of its emergence.
对17名在急性疾病导致昏迷后呈现植物状态特征的儿童的数据进行了分析。其中15名年龄在三岁以下。弥漫性缺氧/缺血（12例）和脑膜炎（4例）是导致昏迷状态的最常见原因。7名儿童死亡，10名幸存者中有9名仍存在严重的神经发育障碍，没有认知功能（随访时间为两个月至五年）。一名儿童在初次患病一年后能够行走，但有中度智力迟钝。研究结果表明，因疾病导致昏迷后出现植物状态的儿童预后不良，去皮层或去大脑反应、眼球游动和自发眨眼可能是其出现的早期指标。
