Maayan M L, Volpert E M, Dawry F
Endocrinology. 1978 Aug;103(2):652-5. doi: 10.1210/endo-103-2-652.
Adenosine, like catecholamines, inhibits the thyroidal T4 release in vitro, when stimulated by TSH,N,O'-dibutyryl cyclic AMP [(Bu) 2cAMP], and phosphodiesterase inhibitors. Unlike catecholamines, the adenosine-induced inhibition is independent of adrenergic receptors. It is postulated that TSH stimulates thyroidal T4 release through a cAMP activated, adenosine-sensitive, protein kinase.
腺苷与儿茶酚胺一样，在受到促甲状腺激素（TSH）、N,O'-二丁酰环磷酸腺苷[（Bu）2cAMP]和磷酸二酯酶抑制剂刺激时，可在体外抑制甲状腺T4释放。与儿茶酚胺不同，腺苷诱导的抑制作用不依赖于肾上腺素能受体。据推测，TSH通过环磷酸腺苷激活的、腺苷敏感的蛋白激酶刺激甲状腺T4释放。
