Borg J
J Neurol Neurosurg Psychiatry. 1980 Oct;43(10):917-24. doi: 10.1136/jnnp.43.10.917.
The aim of this study was to test the reliability of the commonly used blocking technique for measuring the conduction velocity spectrum of the peripheral motor nerve in man, as first described by Hopf in 1962. Electromyographic recordings were carried out with a selectivity permitting identification of single motor unit potentials. The conduction velocity of the single alpha motor axon was determined by a direct technique and by the blocking technique. the refractory period was determined by comparison of the results of these two techniques. The refractory period was studied in relation to the strength of the testing stimulus, axonal conduction velocity, skin temperature and age of the subject. When the strength of the test stimulus increased from 10% to 50% above the axonal threshold, the refractory period decreased from 1.7 to 0.6 ms. An inverse relationship between the axonal conduction velocity and the refractory period was observed. When skin temperature was 4 degrees C subnormal the refractory period was significantly prolonged; at 10 degrees C subnormal it was more than doubled. The same relationship between axonal conduction velocity and the refractory period was observed in both young and elderly subjects. The significance of these findings for the clinical application of the blocking technique is discussed.
本研究的目的是检验1962年霍普夫首次描述的用于测量人体周围运动神经传导速度谱的常用阻滞技术的可靠性。采用具有选择性的肌电图记录，以识别单个运动单位电位。通过直接技术和阻滞技术测定单个α运动轴突的传导速度。通过比较这两种技术的结果来确定不应期。研究了不应期与测试刺激强度、轴突传导速度、皮肤温度和受试者年龄的关系。当测试刺激强度从高于轴突阈值10%增加到50%时，不应期从1.7毫秒降至0.6毫秒。观察到轴突传导速度与不应期呈反比关系。当皮肤温度低于正常4摄氏度时，不应期显著延长；低于正常10摄氏度时，不应期增加一倍以上。在年轻和老年受试者中均观察到轴突传导速度与不应期之间的相同关系。讨论了这些发现对阻滞技术临床应用的意义。
