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组织培养中预防和治疗肝细胞胶原纤维形成的尝试。

An attempt in tissue culture at preventing and treating the collagen fiber formation of liver cells.

作者信息

Katsuta H, Takaoka T

出版信息

Jpn J Exp Med. 1980 Aug;50(4):275-82.

PMID:7441906
Abstract

To prevent and to cure liver cirrhosis, we examined the effect of the ethanol extract of berries of Japanese ampelopsis on the collagen formation of rat liver cells in tissue culture. These cells had been transformed to produce collagen fibers very actively. When added at a time of subcultivation, the extract prevented the formation of collagen fibers. When it was added after the formation of collagen fibers, the fibers were fragmented into fine microfilaments.

摘要

为了预防和治疗肝硬化,我们研究了日本蛇葡萄果实乙醇提取物对组织培养中大鼠肝细胞胶原蛋白形成的影响。这些细胞已被转化为能非常活跃地产生胶原纤维。在传代培养时添加该提取物,可防止胶原纤维的形成。在胶原纤维形成后添加,纤维会破碎成细小的微丝。

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