Pau H
Klin Monbl Augenheilkd. 1980 May;176(5):745-51. doi: 10.1055/s-2008-1057547.
Both "Handmann's optic nerve anomaly" and "Morning Glory Syndrome" are pronounced rearward displacements of the optic disk. The resultant peripapillary scleral staphyloma may be either the cylindrical "Handmann's optic nerve anomaly" or the funnel-shaped "Morning Glory Syndrome". The peripapillary scleral staphyloma is frequently filled to a variable extent with embryonal (Bergmeister papilla), reddish-grey tissue with a white center. The central vessels branching in the depths of the scleral staphyloma then mainly protrude as small vessels at the inner margin of the scleral staphyloma. The optic nerve anomaly is mostly surrounded (in the area of former embryonal tissue?) by circular pigmentation, depigmentation or atrophy of the chorioid of variable extent. "Handmann's optic nerve anomaly" and the "Morning Glory Syndrome" are likely to be variations of the same anomaly.
“汉德曼视神经异常”和“牵牛花综合征”均表现为视盘明显向后移位。由此产生的视乳头周围巩膜葡萄肿可能是圆柱形的“汉德曼视神经异常”,也可能是漏斗状的“牵牛花综合征”。视乳头周围巩膜葡萄肿常不同程度地被胚胎性(贝格迈斯特乳头)、中心呈白色的红灰色组织填充。在巩膜葡萄肿深处分支的中央血管,主要以小血管形式突出于巩膜葡萄肿的内缘。视神经异常大多被不同程度的脉络膜圆形色素沉着、色素脱失或萎缩所包围(在前胚胎组织区域?)。“汉德曼视神经异常”和“牵牛花综合征”可能是同一异常的不同变体。