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Flow dependence of first-order uptake of substances by heterogeneous perfused organs.

作者信息

Bass L

出版信息

J Theor Biol. 1980 Sep 21;86(2):365-76. doi: 10.1016/0022-5193(80)90012-0.

DOI:10.1016/0022-5193(80)90012-0
PMID:7442298
Abstract
摘要

相似文献

1
Flow dependence of first-order uptake of substances by heterogeneous perfused organs.
J Theor Biol. 1980 Sep 21;86(2):365-76. doi: 10.1016/0022-5193(80)90012-0.
2
How small is the functional variability of liver sinusoids?肝血窦的功能变异性有多小？
J Theor Biol. 1979 Dec 21;81(4):761-9. doi: 10.1016/0022-5193(79)90280-7.
3
Importance of flow and haematocrit for metabolic function of perfused rat liver.
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4
Kinetics of galactose uptake by perfused rat livers: applicability of a family of models.灌注大鼠肝脏摄取半乳糖的动力学：一系列模型的适用性
J Theor Biol. 1983 Apr 7;101(3):335-44. doi: 10.1016/0022-5193(83)90142-x.
5
Hepatic phagocytic, metabolic, and blood-flow evaluation by dynamic scintigraphy.通过动态闪烁扫描术评估肝脏吞噬、代谢及血流情况。
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6
Galactose and glucose metabolism in the isolated perfused suckling and adult rat liver.分离灌注的乳鼠和成年大鼠肝脏中的半乳糖和葡萄糖代谢
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7
Evaluation of hepatocellular and Kupffer cell function of the isolated guinea pig liver perfused by a fluorocarbon medium.用氟碳化合物介质灌注的离体豚鼠肝脏的肝细胞和库普弗细胞功能评估。
Gastroenterology. 1978 Feb;74(2 Pt 1):209-14.
8
[Liver blood flow and RES-function after different injuries].[不同损伤后的肝脏血流与网状内皮系统功能]
Nord Med. 1971 Jul 29;86(30):914.
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Effect of sinusoidal perfusion on galactose elimination kinetics in perfused rat liver.正弦灌注对灌注大鼠肝脏中半乳糖消除动力学的影响。
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10
The function of the isolated perfused and the in vivo pig liver.离体灌注猪肝和活体猪肝的功能。
Scand J Gastroenterol Suppl. 1971;9:131-8.

引用本文的文献

1
The pharmacokinetics of the interstitial space in humans.人体间质间隙的药代动力学。
BMC Clin Pharmacol. 2003 Jul 30;3:3. doi: 10.1186/1472-6904-3-3.
2
A nonlinear physiologic pharmacokinetic model: I. Steady-state.一种非线性生理药代动力学模型：I. 稳态
J Pharmacokinet Biopharm. 1985 Feb;13(1):73-92. doi: 10.1007/BF01073657.
3
A dispersion model of hepatic elimination: 2. Steady-state considerations--influence of hepatic blood flow, binding within blood, and hepatocellular enzyme activity.肝脏消除的弥散模型：2. 稳态考量——肝血流量、血液内结合以及肝细胞酶活性的影响
J Pharmacokinet Biopharm. 1986 Jun;14(3):261-88. doi: 10.1007/BF01106707.
4
Models of hepatic elimination: comparison of stochastic models to describe residence time distributions and to predict the influence of drug distribution, enzyme heterogeneity, and systemic recycling on hepatic elimination.
J Pharmacokinet Biopharm. 1988 Feb;16(1):41-83. doi: 10.1007/BF01061862.
5
Clinical applicability of current pharmacokinetic models: splanchnic elimination of 5-fluorouracil in cancer patients.当前药代动力学模型的临床适用性：癌症患者中5-氟尿嘧啶的内脏清除率
J Pharmacokinet Biopharm. 1988 Jun;16(3):229-49. doi: 10.1007/BF01062135.
6
Effect of plasma protein binding on elimination of taurocholate by isolated perfused rat liver: comparison of venous equilibrium, undistributed and distributed sinusoidal, and dispersion models.血浆蛋白结合对离体灌注大鼠肝脏消除牛磺胆酸盐的影响：静脉平衡、非分布和分布性肝血窦以及弥散模型的比较
J Pharmacokinet Biopharm. 1988 Aug;16(4):377-96. doi: 10.1007/BF01062552.
7
Availability predictions by hepatic elimination models for Michaelis-Menten kinetics.基于米氏动力学的肝脏消除模型的可用性预测。
J Pharmacokinet Biopharm. 1989 Dec;17(6):687-719. doi: 10.1007/BF01062125.
8
Influence of unbound fraction and perfusate flow rate on taurocholate elimination by perfused rat liver: applicability of three distributed models.非结合分数和灌注液流速对大鼠肝脏灌注牛磺胆酸盐消除的影响：三种分布模型的适用性
Pharm Res. 1989 Oct;6(10):874-6. doi: 10.1023/a:1015912606260.
9
Axial tissue diffusion can account for the disparity between current models of hepatic elimination for lipophilic drugs.轴向组织扩散可以解释目前亲脂性药物肝脏消除模型之间的差异。
J Pharmacokinet Biopharm. 1992 Feb;20(1):19-61. doi: 10.1007/BF01143185.