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[2,3-二氮杂吩噻嗪的合成。十四。8-乙酰氨基-2H-哒嗪并(4,5-b)(1,4)苯并噻嗪-1(10H)-酮及其异构体8-乙酰氨基-3H-哒嗪并(4,5-b)(1,4)苯并噻嗪-4(10H)-酮的二烷基氨基烷基衍生物]

[Synthesis of 2,3-diazaphenothiazines. XIV. Dialkylaminoalkyl derivatives of 8-acetylamino-2H-pyridazino(4,5b)(1,4)benzothiazine-1(10H)-one and of the isomer 8-acetylamino-3H-pyridazino(4,5b)(1,4)benzothiazine-4(10H)-one].

作者信息

Duro F, Pappalardo F, Vittorio F

出版信息

Farmaco Sci. 1978 Sep;33(9):676-83.

PMID:744264
Abstract

A description is given of some 2 or 3 dialkylaminoalkyl derivatives of 8-acetylamino-2H-pyridazino[4,5-b][1,4]benzothiazin-1(10H)-one (IV a...d) and 8-acetylamino-3H-pyridazino[4,5-b][1,4]benzothiazin-4(10H)-one (VIII a...d). The derivatives were subjected to pharmacological examination.

摘要

描述了8-乙酰氨基-2H-哒嗪并[4,5-b][1,4]苯并噻嗪-1(10H)-酮(IV a...d)和8-乙酰氨基-3H-哒嗪并[4,5-b][1,4]苯并噻嗪-4(10H)-酮(VIII a...d)的一些2或3-二烷基氨基烷基衍生物。对这些衍生物进行了药理学检查。

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1
[Synthesis of 2,3-diazaphenothiazines. XIV. Dialkylaminoalkyl derivatives of 8-acetylamino-2H-pyridazino(4,5b)(1,4)benzothiazine-1(10H)-one and of the isomer 8-acetylamino-3H-pyridazino(4,5b)(1,4)benzothiazine-4(10H)-one].[2,3-二氮杂吩噻嗪的合成。十四。8-乙酰氨基-2H-哒嗪并(4,5-b)(1,4)苯并噻嗪-1(10H)-酮及其异构体8-乙酰氨基-3H-哒嗪并(4,5-b)(1,4)苯并噻嗪-4(10H)-酮的二烷基氨基烷基衍生物]
Farmaco Sci. 1978 Sep;33(9):676-83.
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[Synthesis of 2,3-diazaphenothiazines. XIII. Dialkylaminoalkylic derivatives of 7-acetylamino-2H-pyridazino(4,5-b) (1,4)benzothiazin-1 (1OH)one and of the isomer of 7-acetylamino-3H-pyridazino(4,5-b) (1,4)benzothiazin-4 (1OH)-one].[2,3-二氮杂吩噻嗪的合成。 XIII. 7-乙酰氨基-2H-哒嗪并(4,5-b)(1,4)苯并噻嗪-1(1OH)酮及7-乙酰氨基-3H-哒嗪并(4,5-b)(1,4)苯并噻嗪-4(1OH)酮异构体的二烷基氨基烷基衍生物]
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Synthesis and pharmacological evaluation of 3H-pyridazino[4,5-b][1,4]benzothiazin-4(10H)-one derivatives.3H-哒嗪并[4,5-b][1,4]苯并噻嗪-4(10H)-酮衍生物的合成与药理评价
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Chemical and pharmacological investigations on 2H-pyridazino[4,5-b] [1,4]benzothiazin-1(10H)-one derivatives.
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Farmaco Sci. 1975 Mar;30(3):208-22.
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[Synthesis of 2,3-diazaphenothiazine. XI. 2- and 3-arylderivatives of 10-methyl-2,3-dihydropyridazine /4,5-b/ / 1,4/ benzothiazin-1,4(10H)-dione].[2,3-二氮杂吩噻嗪的合成。XI. 10-甲基-2,3-二氢哒嗪/4,5-b//1,4/苯并噻嗪-1,4(10H)-二酮的2-和3-芳基衍生物]
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[Synthesis of 2,3-diazaphenothiazine. XII. Dialkylaminoalkylic derivatives of 2-phenyl and 3-phenyl-10-methyl-2,3-dihydropyridazino/4,5-b/ /1,4/benzothiazin-1,4 (10 H)-dione].[2,3-二氮杂吩噻嗪的合成。十二。2-苯基和3-苯基-10-甲基-2,3-二氢哒嗪并/4,5-b//1,4/苯并噻嗪-1,4(10H)-二酮的二烷基氨基烷基衍生物]
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[Synthesis of 2,3-diazaphenothiazine. X. 7- and 8-nitroderivatives of 1- keto and of 4-keto-2,3-diazaphenothiazine and their mixtures of oxidation on 5].[2,3-二氮杂吩噻嗪的合成。X。1-酮基和4-酮基-2,3-二氮杂吩噻嗪的7-和8-硝基衍生物及其在5位的氧化混合物]
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Synthesis and antibacterial activity of some new mesoionics.一些新型介离子化合物的合成与抗菌活性
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Antitumor activity of phenothiazine-related compounds.吩噻嗪类相关化合物的抗肿瘤活性。
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