Impicciatore M, Bertaccini G, Chiavarini M, Molina E, Vitali T, Bordi F
Farmaco Sci. 1978 Sep;33(9):696-704.
Compound 2-(5-methyl-4-imidazolyl)-1-methylethylamine was tested on different preparations for its histamine-like activity. It was found to markedly affect H2 receptors and at the same time to be practically devoid of any activity on H1 receptors. This high selectivity of action indicates that this compound may represent a useful tool for characterizing the distribution of H2 and H1 receptor sites.
对化合物2-(5-甲基-4-咪唑基)-1-甲基乙胺的组胺样活性在不同制剂上进行了测试。发现它对H2受体有显著影响,同时对H1受体几乎没有任何活性。这种高选择性作用表明该化合物可能是表征H2和H1受体位点分布的有用工具。