真核染色体中特定DNA序列的识别。
Recognition of specific DNA sequences in eukaryotic chromosomes.
作者信息
Weintraub H
出版信息
Nucleic Acids Res. 1980 Oct 24;8(20):4745-53. doi: 10.1093/nar/8.20.4745.
Abstract
The packaging of DNA into chromatin probably places certain restrictions on how specific DNA sequences can be recognized by DNA sequence specific recognition proteins (SRP). Several unique features of this type of interaction are discussed. Specifically, as a consequence of the coiling of the DNA about a histone core, it is proposed that DNA recognition sites will be compound and that each element of the compound recognition site will be about 10 - 20 b.p. in length and distributed at approximately 80 b.p. intervals--the periodicity of the DNA wrapping around the nucleosome.
摘要
DNA包装成染色质可能对特定DNA序列特异性识别蛋白（SRP）识别特定DNA序列的方式施加了某些限制。本文讨论了这种相互作用类型的几个独特特征。具体而言，由于DNA围绕组蛋白核心盘绕，有人提出DNA识别位点将是复合的，并且复合识别位点的每个元件长度约为10 - 20个碱基对，且以大约80个碱基对的间隔分布——这是DNA围绕核小体缠绕的周期性。
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本文引用的文献
1
Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I.由DNA酶I引入的珠蛋白染色质结构域中的组织特异性DNA切割。
Cell. 1980 Jun;20(2):451-60. doi: 10.1016/0092-8674(80)90631-5.
2
Nucleosome structure.核小体结构。
Annu Rev Biochem. 1980;49:1115-56. doi: 10.1146/annurev.bi.49.070180.005343.
3
Solenoidal model for superstructure in chromatin.染色质上层结构的螺线管模型。
Proc Natl Acad Sci U S A. 1976 Jun;73(6):1897-901. doi: 10.1073/pnas.73.6.1897.
4
Structure of nucleosome core particles of chromatin.染色质核小体核心颗粒的结构。
Nature. 1977 Sep 1;269(5623):29-36. doi: 10.1038/269029a0.
5
Nucleosome arcs and helices.核小体弧和螺旋。
Science. 1978 Oct 20;202(4365):280-6. doi: 10.1126/science.694532.
6
Nucleosomal DNA is digested to repeats of 10 bases by exonuclease III.核小体DNA被核酸外切酶III消化为10个碱基的重复序列。
Cell. 1978 Feb;13(2):281-93. doi: 10.1016/0092-8674(78)90197-6.
7
Why genes in pieces?为什么基因是断裂的？
Nature. 1978 Feb 9;271(5645):501. doi: 10.1038/271501a0.
8
DNA methylation: correlation with DNase I sensitivity of chicken ovalbumin and conalbumin chromatin.DNA甲基化：与鸡卵清蛋白和伴清蛋白染色质的DNase I敏感性的相关性
Nucleic Acids Res. 1979 Dec 20;7(8):2105-13. doi: 10.1093/nar/7.8.2105.
9
A phase relationship associates tRNA structural gene sequences with nucleosome cores.
Cell. 1979 Dec;18(4):1173-83. doi: 10.1016/0092-8674(79)90230-7.
10
Higher-order structures of chromatin in solution.溶液中染色质的高阶结构。
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