小剂量甘草诱发的严重低钾血症伴麻痹
Severe hypokalaemia with paralysis induced by small doses of liquorice.
作者信息
Cumming A M, Boddy K, Brown J J, Fraser R, Lever A F, Padfield P L, Robertson J I
出版信息
Postgrad Med J. 1980 Jul;56(657):526-9. doi: 10.1136/pgmj.56.657.526.
Abstract
A patient, who presented with a flaccid quadriplegia due to profound hypokalaemia, is described. Hypokalaemia and myoglobinuria were caused by the ingestion of small amounts of liquorice contained in a laxative preparation. Subsequent controlled administration of small amounts of this preparation induced marked hypokalaemia. This was associated with sodium retention and potassium loss confirming a mineralocorticoid-like action. The sodium retention was associated with suppression of plasma levels of renin and aldosterone.
摘要
本文描述了一名因严重低钾血症而出现弛缓性四肢瘫痪的患者。低钾血症和肌红蛋白尿是由服用一种缓泻制剂中含有的少量甘草引起的。随后对该制剂进行小剂量的控制性给药诱发了明显的低钾血症。这与钠潴留和钾丢失相关，证实了类似盐皮质激素的作用。钠潴留与血浆肾素和醛固酮水平的抑制有关。
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Hypokalaemia, flaccid quadruparesis, and myoglobinuria with carbenoxolone (biogastrone).低血钾、弛缓性四肢瘫以及服用生胃酮（胃溃宁）后的肌红蛋白尿。
Br Med J. 1966 Jun 25;1(5503):1581-2. doi: 10.1136/bmj.1.5503.1581.
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Hypokalemic myopathy with myoglobinuria associated with licorice ingestion.与摄入甘草相关的低钾性肌病伴肌红蛋白尿。
N Engl J Med. 1966 Mar 17;274(11):602-6. doi: 10.1056/NEJM196603172741104.
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Muscle paresis and hypokalemia after treatment with duogastrone.使用双层片治疗后出现肌肉轻瘫和低钾血症。
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Licorice-induced pseudoaldosteronism. Hypertension, hypokalemia, aldosteronopenia, and suppressed plasma renin activity.
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