Cumming A M, Boddy K, Brown J J, Fraser R, Lever A F, Padfield P L, Robertson J I
Postgrad Med J. 1980 Jul;56(657):526-9. doi: 10.1136/pgmj.56.657.526.
A patient, who presented with a flaccid quadriplegia due to profound hypokalaemia, is described. Hypokalaemia and myoglobinuria were caused by the ingestion of small amounts of liquorice contained in a laxative preparation. Subsequent controlled administration of small amounts of this preparation induced marked hypokalaemia. This was associated with sodium retention and potassium loss confirming a mineralocorticoid-like action. The sodium retention was associated with suppression of plasma levels of renin and aldosterone.
本文描述了一名因严重低钾血症而出现弛缓性四肢瘫痪的患者。低钾血症和肌红蛋白尿是由服用一种缓泻制剂中含有的少量甘草引起的。随后对该制剂进行小剂量的控制性给药诱发了明显的低钾血症。这与钠潴留和钾丢失相关，证实了类似盐皮质激素的作用。钠潴留与血浆肾素和醛固酮水平的抑制有关。
