Russell P
Placenta. 1980 Jul-Sep;1(3):227-44. doi: 10.1016/s0143-4004(80)80005-1.
All placentae delivered in a large obstetrics hospital in a two-year period were examined macroscopically and histologically. Of 7505 consecutive singleton placentae, chronic focal placental villitis of unknown aetiology (VUE) was found in 575 (7.6 per cent). The clinical correlates of these cases have been published previously (Russell, 1979). The present report details histological spectra of severity and distribution of the lesions, cell types within the inflammatory foci and secondary changes consequent upon local reduction in both maternal and fetal blood flow through the placenta. Histological findings tend to support direct extension of the infection from uterine sources rather than haematogenous inoculation of the placenta. The clinical sequelae for the infant appear to correlate positively with the severity of the villitis process.
在两年时间里，对一家大型产科医院分娩的所有胎盘进行了宏观和组织学检查。在7505例连续的单胎胎盘中，发现575例（7.6%）存在病因不明的慢性局灶性胎盘绒毛炎（VUE）。这些病例的临床相关情况此前已发表（拉塞尔，1979年）。本报告详细描述了病变的严重程度和分布的组织学谱、炎症灶内的细胞类型以及由于通过胎盘的母体和胎儿血流局部减少而导致的继发性变化。组织学结果倾向于支持感染从子宫来源直接蔓延，而不是胎盘的血源性接种。婴儿的临床后遗症似乎与绒毛炎过程的严重程度呈正相关。
