Opgenoorth E, Lenz G, Sperlich S, Wytek R
Pharmakopsychiatr Neuropsychopharmakol. 1980 Jul;13(4):182-99. doi: 10.1055/s-2007-1019631.
A representative sample of patients under long-term lithium therapy was examined with respect to performance in reaction task, mood, and attitude toward lithium therapy. Reaction time to simple acoustic or visual stimuli as well as reactivity in complex settings under power- and speed-conditions requiring psychomotoric response represent the bulk of the data. Significant effects of additional medication, sex and duration of lithium therapy are assessed by univariate and multivariate data analysis. A hierarchic cluster analysis results in 5 well interpretable clusters. The clusters, furthermore, demonstrate the importance of attitude and other psychological variable, e.g. morning-/evening-type.
对长期接受锂盐治疗的患者进行了代表性抽样，考察了他们在反应任务中的表现、情绪以及对锂盐治疗的态度。对简单听觉或视觉刺激的反应时间，以及在需要精神运动反应的功率和速度条件下复杂环境中的反应性，构成了大部分数据。通过单变量和多变量数据分析评估了辅助用药、性别和锂盐治疗持续时间的显著影响。层次聚类分析产生了5个易于解释的聚类。此外，这些聚类还证明了态度和其他心理变量（如晨型/夜型）的重要性。
