Hammer B
Radiologe. 1980 Oct;20(10):478-84.
A report is given on lumbosacral myelography (radiculography) with special reference to technique and contrast agents used--all based on clinical and experimental experience. The use of water-soluble contrast material is recommended. The non-ionic metrizamide ("Amipaque") seems to be the agent of choice because of its inertia to cause adverse leptomeningeal changes. Also, another non-ionic contrast agent "Jopamidol" seems very promising. The non-ionic contrast media are to be applied in a concentration isotonic to that of the CSF; this is also sufficient to even show fine structures. Though the new contrast media exhibit low neurotoxicity, they are not inert. Therefore, the application of very careful technique and the limitation of amount and concentration of the contrast medium to as low as possible are indispensable. The radiation dose to spine and gonads was found to be tolerable.
本文基于临床和实验经验,报告了腰骶部脊髓造影(神经根造影),特别提及了所使用的技术和造影剂。推荐使用水溶性造影剂。非离子型甲泛葡胺(“阿米培克”)似乎是首选药物,因为它不易引起软脑膜的不良反应。此外,另一种非离子型造影剂“碘海醇”似乎也很有前景。非离子型造影剂应以与脑脊液等渗的浓度使用;这甚至足以显示精细结构。尽管新型造影剂神经毒性较低,但并非完全无害。因此,采用非常谨慎的技术以及将造影剂的用量和浓度限制在尽可能低的水平是必不可少的。对脊柱和性腺的辐射剂量被认为是可耐受的。