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骨盆骨髓选择性发育不全。

Selective hypoplasia of pelvic bone marrow.

作者信息

Ferrant A, Rodhain J, Cordier A, Symann M, Michaux J L, Sokal G

出版信息

Scand J Haematol. 1980 Jul;25(1):12-8. doi: 10.1111/j.1600-0609.1981.tb01358.x.

DOI:10.1111/j.1600-0609.1981.tb01358.x
PMID:7444370
Abstract

6 patients with thrombocytopenia and anaemia had fatty marrow replacement at the site of an iliac crest. 52Fe scans showed marked abnormalities of bone marrow distribution. Particularly, the uptake of radioiron into the pelvis was almost absent. The sternal marrow was cellular. Studies of the bone marrow which included cytology, histology and electron microscopy failed to reveal why the pelvic marrow was aplastic. Occasional vascular lesions could not seen in the iliac crest bone marrow sections. The cellular morphology showed slight maturation abnormalities. Ferrokinetics were consistent with erythroid marrow hypoplasia. The pelvic and sternal marrow cellularity in patients with pancytopenia may not be representative of the cellularity of the whole marrow, and the pelvic marrow especially may be prone to aplasia.

摘要

6例血小板减少症和贫血患者在髂嵴部位出现脂肪骨髓替代。52铁扫描显示骨髓分布明显异常。特别是,骨盆几乎没有放射性铁的摄取。胸骨骨髓有细胞。包括细胞学、组织学和电子显微镜在内的骨髓研究未能揭示骨盆骨髓发育不全的原因。在髂嵴骨髓切片中未发现偶尔的血管病变。细胞形态显示有轻微的成熟异常。铁动力学与红系骨髓发育不全一致。全血细胞减少症患者的骨盆和胸骨骨髓细胞性可能不代表整个骨髓的细胞性,尤其是骨盆骨髓可能易于发育不全。

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