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用猪黏膜和牛肺肝素治疗期间血小板减少症的发生率较低。

Low incidence of thrombocytopenia during treatment with hog mucosa and beef lung heparin.

作者信息

Eika C, Godal H C, Laake K, Hamborg T

出版信息

Scand J Haematol. 1980 Jul;25(1):19-24. doi: 10.1111/j.1600-0609.1981.tb01359.x.

DOI:10.1111/j.1600-0609.1981.tb01359.x
PMID:7444371
Abstract

129 patients with thrombosis were treated with heparin for 5 d and followed with platelet counts and coagulation examinations. Of 77 patients treated with 2 different brands of hog mucosa heparin, only 1 developed persistent thrombocytopenia below 100 X 10(9)/1. Of 52 patients treated with beef lung heparin, 1 patient developed thrombocytopenia. No patient developed intravascular coagulation or activated fibrinolysis during heparin treatment.

摘要

129例血栓形成患者接受肝素治疗5天,并监测血小板计数和凝血检查。在77例接受两种不同品牌猪黏膜肝素治疗的患者中,只有1例出现持续血小板减少,低于100×10⁹/L。在52例接受牛肺肝素治疗的患者中,有1例出现血小板减少。在肝素治疗期间,没有患者发生血管内凝血或激活纤维蛋白溶解。

相似文献

1
Low incidence of thrombocytopenia during treatment with hog mucosa and beef lung heparin.用猪黏膜和牛肺肝素治疗期间血小板减少症的发生率较低。
Scand J Haematol. 1980 Jul;25(1):19-24. doi: 10.1111/j.1600-0609.1981.tb01359.x.
2
An unusually prolonged case of heparin-induced thrombocytopenia and disseminated intravascular coagulation.一例罕见的肝素诱导的血小板减少症和弥散性血管内凝血的长期病例。
Haematologica. 1992 Mar-Apr;77(2):174-6.
3
Heparin-induced thrombocytopenia: a prospective study.肝素诱导的血小板减少症:一项前瞻性研究。
Am J Hematol. 1984;17(4):349-53. doi: 10.1002/ajh.2830170404.
4
[Significance and incidence of type II heparin-induced thrombocytopenia. A prospective study].[II型肝素诱导的血小板减少症的意义与发病率。一项前瞻性研究]
Zentralbl Chir. 2001 Jan;126(1):39-43. doi: 10.1055/s-2001-11718.
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Heparin-associated thrombocytopenia: a comparison of three heparin preparations.
N Engl J Med. 1980 Oct 16;303(16):902-7. doi: 10.1056/NEJM198010163031602.
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[Heparin-induced thrombocytopenia in hemodialysis. Case report and review of the literature].[血液透析中肝素诱导的血小板减少症。病例报告及文献综述]
Nefrologia. 2006;26(6):734-7.
7
Thrombocytopenia found uncommonly during heparin therapy.肝素治疗期间血小板减少症并不常见。
JAMA. 1979 Jun 1;241(22):2396-7.
8
[Heparin-induced thrombocytopenia and thrombosis. Thrombosis as an early cardinal symptom of heparin allergy].肝素诱导的血小板减少症和血栓形成。血栓形成作为肝素过敏的早期主要症状
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Thrombocytopenia in a prospective, randomized, double-blind trial of bovine and porcine heparin.牛肝素和猪肝素前瞻性随机双盲试验中的血小板减少症
Am J Med Sci. 1984 Sep;288(2):60-4. doi: 10.1097/00000441-198409000-00003.
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[Thromboembolic events in heparin-induced thrombocytopenia].肝素诱导的血小板减少症中的血栓栓塞事件
Harefuah. 1994 Dec 1;127(11):448-50, 503.

引用本文的文献

1
Unfractionated heparin versus low molecular weight heparins for avoiding heparin-induced thrombocytopenia in postoperative patients.普通肝素与低分子量肝素用于预防术后患者肝素诱导的血小板减少症的比较
Cochrane Database Syst Rev. 2017 Apr 21;4(4):CD007557. doi: 10.1002/14651858.CD007557.pub3.
2
Why is the platelet count low: should I be concerned about heparin-induced thrombocytopenia?血小板计数为何偏低:我应该担心肝素诱导的血小板减少症吗?
J Pediatr Pharmacol Ther. 2012 Jan;17(1):2-6. doi: 10.5863/1551-6776-17.1.2.
3
Thrombocytopenia induced by pulmonary artery flotation catheters. A prospective study.
Intensive Care Med. 1984;10(1):29-31. doi: 10.1007/BF00258065.