Ballogh Z, Whaley K
Scott Med J. 1980 Jul;25(3):187-95. doi: 10.1177/003693308002500303.
Hereditary angio-oedema is a genetically-determined disease. Usually the disease is due to a deficiency of C1-inhibitor or less commonly to the production of a functionally inactive molecule. The pathogenesis and clinical features of the disease are reviewed, and discussed in relation to the homeostatic role of C1 inhibitor. Finally the therapeutic approach to the disease is described and the scientific bases for the newer therapeutic discussed.
遗传性血管性水肿是一种由基因决定的疾病。通常，该病是由于C1抑制物缺乏所致，较少情况下是由于产生了功能失活的分子。本文综述了该病的发病机制和临床特征，并结合C1抑制物的稳态作用进行了讨论。最后描述了该病的治疗方法，并讨论了新型治疗方法的科学依据。
