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多剂量皮下注射钩虫抑素对猫棘颚口线虫移行期的化疗

Chemotherapy of feline Gnathostoma spinigerum migrating stage with multiple subcutaneous doses of ancylol.

作者信息

Daengsvang S

出版信息

Southeast Asian J Trop Med Public Health. 1980 Sep;11(3):359-62.

PMID:7444577
Abstract

Twelve doses of Ancylol Disophenol at 0.05 ml per pound body weight administered subcutaneously was shown to be an effective chemotherapeutic agent against migrating stage of G. spinigerum in cats. A further investigation is required to determine whether this regimen is the minimum effective therapeutic dosage. None of eight cats treated with 12 doses of 0.02 to 0.05 ml per pound body weight showed signs or symptoms of toxicity due to the treatment and there were not gross pathological changes of the organs observed on necropsy of the animals.

摘要

每磅体重皮下注射0.05毫升的十二剂双酚胺甲酚被证明是一种有效的化学治疗剂,可对抗猫体内棘颚口线虫的移行期。需要进一步研究以确定该方案是否为最低有效治疗剂量。用每磅体重0.02至0.05毫升的十二剂治疗的八只猫中,没有一只表现出因治疗导致的毒性体征或症状,并且在对动物进行尸检时未观察到器官的明显病理变化。

相似文献

1
Chemotherapy of feline Gnathostoma spinigerum migrating stage with multiple subcutaneous doses of ancylol.多剂量皮下注射钩虫抑素对猫棘颚口线虫移行期的化疗
Southeast Asian J Trop Med Public Health. 1980 Sep;11(3):359-62.
2
A preliminary study of chemotherapy of Gnathostoma spinigerum infections in cats with ancylol disophenol (2,6-diiodo-4-nitrophenol).用双碘酚(2,6 - 二碘 - 4 - 硝基苯酚)对感染棘颚口线虫的猫进行化疗的初步研究。
Southeast Asian J Trop Med Public Health. 1971 Sep;2(3):359-61.
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Gnathostomiasis in Southeast Asia.东南亚的颚口线虫病。
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Study on the diagnosis of Gnathostoma infection in cats by radioimmunoassay.用放射免疫分析法诊断猫颚口线虫感染的研究
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Evaluation of granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats.
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Ultrastructural effects of albendazole on the body wall of Gnathostoma spinigerum third stage larvae.阿苯达唑对棘颚口线虫第三期幼虫体壁的超微结构影响
Southeast Asian J Trop Med Public Health. 2009 Nov;40(6):1199-207.
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Scanning electron microscopy of the cuticular armature of the nematode Gnathostoma spinigerum Owen, 1836 from cats in Laos.老挝猫体内1836年欧文描述的棘颚口线虫角质层结构的扫描电子显微镜观察
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Pila ampullacea and Pomacea canaliculata, as new paratenic hosts of Gnathostoma spinigerum.福寿螺和福寿螺,作为棘颚口线虫的新转续宿主。
Southeast Asian J Trop Med Public Health. 2009 Mar;40(2):243-6.
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Effects of albendazole on Gnathostoma spinigerum in mice.阿苯达唑对小鼠棘颚口线虫的作用。
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Characterization of the humoral immune response against Gnathostoma binucleatum in patients clinically diagnosed with gnathostomiasis.对临床诊断为颚口线虫病患者的抗颚口线虫体液免疫反应的特征分析。
Am J Trop Med Hyg. 2012 Jun;86(6):988-92. doi: 10.4269/ajtmh.2012.11-0741.
2
Eosinophilic meningitis and radiculomyelitis in Thailand, caused by CNS invasion of Gnathostoma spinigerum and Angiostrongylus cantonensis.泰国因棘颚口线虫和广州管圆线虫侵犯中枢神经系统而导致的嗜酸性粒细胞性脑膜炎和脊神经根脊髓炎。
J Neurol Neurosurg Psychiatry. 1988 Jan;51(1):80-7. doi: 10.1136/jnnp.51.1.80.