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多剂量皮下注射钩虫抑素对猫棘颚口线虫移行期的化疗

Chemotherapy of feline Gnathostoma spinigerum migrating stage with multiple subcutaneous doses of ancylol.

作者信息

Daengsvang S

出版信息

Southeast Asian J Trop Med Public Health. 1980 Sep;11(3):359-62.

PMID:7444577
Abstract

Twelve doses of Ancylol Disophenol at 0.05 ml per pound body weight administered subcutaneously was shown to be an effective chemotherapeutic agent against migrating stage of G. spinigerum in cats. A further investigation is required to determine whether this regimen is the minimum effective therapeutic dosage. None of eight cats treated with 12 doses of 0.02 to 0.05 ml per pound body weight showed signs or symptoms of toxicity due to the treatment and there were not gross pathological changes of the organs observed on necropsy of the animals.

摘要

每磅体重皮下注射0.05毫升的十二剂双酚胺甲酚被证明是一种有效的化学治疗剂,可对抗猫体内棘颚口线虫的移行期。需要进一步研究以确定该方案是否为最低有效治疗剂量。用每磅体重0.02至0.05毫升的十二剂治疗的八只猫中,没有一只表现出因治疗导致的毒性体征或症状,并且在对动物进行尸检时未观察到器官的明显病理变化。

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