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1
Genetic variation at a locus (TAM-1) for submaxillary gland protease in the mouse and its location on chromosome No. 7.小鼠下颌下腺蛋白酶基因座（TAM-1）的遗传变异及其在7号染色体上的定位。
Genetics. 1978 Dec;90(4):713-24. doi: 10.1093/genetics/90.4.713.
2
Prt-4 and Prt-5: new constituents of a gene cluster on chromosome 7 coding for esterproteases in the submandibular gland of the house mouse (Mus musculus).Prt - 4和Prt - 5：家鼠（小家鼠）下颌下腺中编码酯蛋白酶的7号染色体上一个基因簇的新成分。
Biochem Genet. 1981 Jun;19(5-6):431-44. doi: 10.1007/BF00484616.
3
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4
Location on chromosome 1 of Rnr, a gene that regulates renin in the submaxillary gland of the mouse.Rnr基因位于小鼠颌下腺中调控肾素的基因在1号染色体上的位置。
Proc Natl Acad Sci U S A. 1978 Nov;75(11):5623-6. doi: 10.1073/pnas.75.11.5623.
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Genetic control of renin activity in the submaxillary gland of the mouse.
Proc Natl Acad Sci U S A. 1977 Mar;74(3):1185-9. doi: 10.1073/pnas.74.3.1185.
6
Genetic regulation of thermostability of mouse submaxillary gland renin.小鼠颌下腺肾素热稳定性的遗传调控
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7
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8
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9
Genetic variation for prolidase (PEP-4) in the mouse maps near the gene for glucosephosphate isomerase (GPI-1) on chromosome 7.小鼠中脯氨酰肽酶（PEP - 4）的基因变异定位在7号染色体上葡萄糖磷酸异构酶（GPI - 1）基因附近。
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Genetic variation of an intestinal leucine arylaminopeptidase (Lap-1) in the mouse and its location on chromosome 9.小鼠肠道亮氨酸芳基氨肽酶（Lap-1）的遗传变异及其在9号染色体上的定位。
Biochem Genet. 1975 Oct;13(9-10):511-8. doi: 10.1007/BF00484910.

引用本文的文献

1
Localization of Shaw-related K+ channel genes on mouse and human chromosomes.肖氏相关钾离子通道基因在小鼠和人类染色体上的定位。
Mamm Genome. 1993 Dec;4(12):711-5. doi: 10.1007/BF00357794.
2
Evolutionary conservation of linkage groups: additional evidence from murid and cricetid rodents.连锁群的进化保守性：来自鼠科和仓鼠科啮齿动物的更多证据。
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3
Genetic analysis of protein variations in Mus musculus using two-dimensional electrophoresis.利用二维电泳对小家鼠蛋白质变异进行遗传分析。
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4
Genetic variation for prolidase (PEP-4) in the mouse maps near the gene for glucosephosphate isomerase (GPI-1) on chromosome 7.小鼠中脯氨酰肽酶（PEP - 4）的基因变异定位在7号染色体上葡萄糖磷酸异构酶（GPI - 1）基因附近。
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5
Genetic variation in esteroproteases in the mouse submandibular gland.
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6
Prt-4 and Prt-5: new constituents of a gene cluster on chromosome 7 coding for esterproteases in the submandibular gland of the house mouse (Mus musculus).Prt - 4和Prt - 5：家鼠（小家鼠）下颌下腺中编码酯蛋白酶的7号染色体上一个基因簇的新成分。
Biochem Genet. 1981 Jun;19(5-6):431-44. doi: 10.1007/BF00484616.
7
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8
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9
Linkage and polymorphism of a gene controlling lactate dehydrogenase in the rat.
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10
Mapping of the genes for tubular basement membrane antigen and a submaxillary gland protease in the rat.大鼠肾小管基底膜抗原和下颌下腺蛋白酶基因的定位
Immunogenetics. 1984;20(2):117-23. doi: 10.1007/BF00364483.

本文引用的文献

1
Inbreeding and Linkage.近亲繁殖与连锁
Genetics. 1931 Jul;16(4):357-74. doi: 10.1093/genetics/16.4.357.
2
Biochemical and histochemical observations on the sexual dimorphism of mice submaxillary glands.小鼠颌下腺性别二态性的生化与组织化学观察
J Cell Comp Physiol. 1949 Aug;34(1):129-58, incl 6 pl. doi: 10.1002/jcp.1030340109.
3
Testosterone induction of estero-proteolytic activity in the mouse submaxillary gland.睾酮诱导小鼠颌下腺酯解活性的研究
Biochim Biophys Acta. 1967 Jul 11;139(2):372-81. doi: 10.1016/0005-2744(67)90041-1.
4
Proteases from mouse submaxillary gland.
Biochem Biophys Res Commun. 1969 Jul 7;36(1):156-65. doi: 10.1016/0006-291x(69)90663-9.
5
Linkage analyses using biochemical variants in mice. I. Linkage of the hemoglobin beta-chain and glucosephosphate isomerase loci.利用小鼠生化变异进行连锁分析。I. 血红蛋白β链与葡萄糖磷酸异构酶基因座的连锁
Biochem Genet. 1969 Oct;3(5):507-15. doi: 10.1007/BF00485611.
6
Sex-reversed mice: XX and XO males.性反转小鼠：XX和XO雄性小鼠。
Cytogenetics. 1971;10(5):318-37. doi: 10.1159/000130151.
7
Linkage of genes controlling the rate of synthesis and structure of aminolevulinate dehydratase.控制δ-氨基-γ-酮戊酸脱水酶合成速率和结构的基因的连锁
Science. 1971 Sep 24;173(4003):1245-6. doi: 10.1126/science.173.4003.1245.
8
A morphological and histochemical evaluation of sexual dimorphism in androgen-insensitive pseudohermaphroditic mice.雄激素不敏感假两性畸形小鼠性别二态性的形态学和组织化学评估
Anat Rec. 1972 Nov;174(3):361-9. doi: 10.1002/ar.1091740307.
9
Nerve growth factor from mouse submaxillary gland: amino acid sequence.来自小鼠颌下腺的神经生长因子：氨基酸序列。
Proc Natl Acad Sci U S A. 1971 Oct;68(10):2417-20. doi: 10.1073/pnas.68.10.2417.
10
Proteolytic processing in the biosynthesis of insulin and other proteins.胰岛素及其他蛋白质生物合成中的蛋白水解加工
Fed Proc. 1974 Oct;33(10):2105-15.

小鼠下颌下腺蛋白酶基因座（TAM-1）的遗传变异及其在7号染色体上的定位。

Genetic variation at a locus (TAM-1) for submaxillary gland protease in the mouse and its location on chromosome No. 7.

作者信息

Skow L C

出版信息

Genetics. 1978 Dec;90(4):713-24. doi: 10.1093/genetics/90.4.713.

DOI:10.1093/genetics/90.4.713
PMID:744473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213915/
Abstract

Electrophoretic and activity variants for a testosterone-induced esteroprotease have been discovered in submaxillary glands from inbred strains of mice. The enzyme is tentatively designated tamase [TAM-1] and the variant genetic locus is Tam-1. The alleles Tam-1a and Tam-1b determine electrophoretically distinct zones of tamase activity, while Tam-lc produces no detectable enzyme activity. Data from recombinant inbred strains and B6AF1 X B6 and B6D2F1 X B6 backcrosses established linkage of Tam-1 to glucose phosphate isomerase (Gpi-1), pink-eyed dilution [p] and beta-hemoglobin (Hbb) on chromosome 7. The gene order is Gpi-1--Tam-1--p--HBB. Analysis of congenic resistant strains indicates that Tam-1 is closely linked to the minor histocompatibility locus, H-4. TAM-1 was not cross-reactive with antisera to mouse nerve growth factor, submaxillary renin, or tamases A and D.

摘要

在近交系小鼠的颌下腺中发现了一种睾酮诱导的酯蛋白酶的电泳变体和活性变体。该酶暂定为tamase [TAM-1]，变体基因座为Tam-1。等位基因Tam-1a和Tam-1b决定了tamase活性的电泳不同区域，而Tam-lc不产生可检测到的酶活性。来自重组近交系以及B6AF1×B6和B6D2F1×B6回交的数据确定了Tam-1与7号染色体上的葡萄糖磷酸异构酶（Gpi-1）、粉红眼稀释基因[p]和β-血红蛋白（Hbb）的连锁关系。基因顺序为Gpi-1--Tam-1--p--HBB。对同源抗性品系的分析表明，Tam-1与次要组织相容性位点H-4紧密连锁。TAM-1与针对小鼠神经生长因子、颌下肾素或tamases A和D的抗血清无交叉反应。