Sato A, Ishioka K, Kobiyama M, Goto M, Asaki S, Umetsu Y, Toyohara T, Sato M, Hanzawa K, Ogashiwa K, Goto Y, Wakasa H, Takeda T, Irumagawa H, Tsuda Y, Aizawa A
Tohoku J Exp Med. 1980 Oct;132(2):213-23. doi: 10.1620/tjem.132.213.
The cytological findings in 7 cases of leiomyoma and 4 cases of leiomyosarcoma can be summarized as follows: For differential diagnosis of these lesions, in comparison with leiomyoma cells, leiomyosarcoma cells were found to have 1) increased minor axis diameters of the nuclei and nuclear anisokaryosis, 2) dark nuclear staining, 3) enlarged and darkly stained chromocenters, 4) dark staining and thickening of the nuclear rim, 5) enlargement of nuclear clear areas, 6) increased numbers of oval nuclei and greater pleomorphism, 7) an increase in size and number of the nucleoli, 8) a strong tendency for cell atypism, such as anisocytosis and pleomorphism. In the light of these findings, it is believed that differential diagnosis is indeed possible.
7例平滑肌瘤和4例平滑肌肉瘤的细胞学检查结果总结如下：为鉴别诊断这些病变，与平滑肌瘤细胞相比，平滑肌肉瘤细胞具有以下特征：1）核短径增大及核大小不等；2）核染色深；3）染色中心增大且染色深；4）核边缘染色深且增厚；5）核透明区增大；6）椭圆形核数量增多且多形性更明显；7）核仁大小和数量增加；8）细胞异型性明显增强，如细胞大小不等和多形性。根据这些发现，认为确实可以进行鉴别诊断。
