Pugachev M K
Tsitologiia. 1980 Nov;22(11):1368-71.
It has been shown for the first time that the size of adrenocytes and of their nuclei does not change in the adrenal medulla on the state of motor excitation, and decreases at the heat stroke under conditions of acute overheating. According to Bennighoff (1950), the decrease of nuclear volume suggests the weakness of the adrenocyte secretory activity. But in reality the specific activity of adrenocytes may increase at hyperthermy, which contradicts to the hypothesis in question. Such a contradiction may be explained by the fact of adrenocyte dehydration under the influence of the external heat. It may result in a decrease in the nuclear volume irrespective of the functional state of the nuclei. The secretory activity of adrenocytes can be evaluated on the basis of the changed relation in the nuclear number of varying volume corresponding to different steps of the secretory cycle.
首次表明，在运动兴奋状态下肾上腺髓质中肾上腺细胞及其细胞核的大小不变，而在急性过热条件下中暑时则减小。根据本尼霍夫（1950年）的研究，核体积减小表明肾上腺细胞分泌活动减弱。但实际上，肾上腺细胞的比活性在高温时可能会增加，这与上述假设相矛盾。这种矛盾可以用外部热量影响下肾上腺细胞脱水这一事实来解释。这可能导致核体积减小，而与细胞核的功能状态无关。肾上腺细胞的分泌活动可以根据对应于分泌周期不同阶段的不同体积的核数量的变化关系来评估。
