Flint A P, Forsling M L, Mitchell M D
Horm Metab Res. 1978 Nov;10(6):545-7. doi: 10.1055/s-0028-1093388.
The role of oxytocin in the increase in utero-ovarian venous prostaglandin F (PGF) level caused by vaginal distension was investigated by using lumbar epidural anaesthesia to block the oxytocin secretion reflex. Whereas vaginal distension raised jugular venous oxytocin and utero-ovarian venous PGF levels in untreated sheep, neither response occurred after lumbar anaesthesia. Lumbar anaesthesia had no effect on the rise in utero-ovarian venous PGF level caused by administered oxytocin. These findings support the suggestion that a reflex release of oxytocin is involved in the elevation of utero-ovarian venous PGF observed after vaginal distension in parturient sheep.
通过使用腰段硬膜外麻醉来阻断催产素分泌反射，研究了催产素在阴道扩张引起的子宫 - 卵巢静脉前列腺素F（PGF）水平升高中的作用。在未处理的绵羊中，阴道扩张会提高颈静脉催产素和子宫 - 卵巢静脉PGF水平，但在腰段麻醉后这两种反应均未出现。腰段麻醉对注射催产素引起的子宫 - 卵巢静脉PGF水平升高没有影响。这些发现支持了这样的观点，即分娩期绵羊阴道扩张后观察到的子宫 - 卵巢静脉PGF升高部分涉及催产素的反射性释放。
