绵羊子宫 - 卵巢循环中前列腺素F - 2α的动态研究。
Dynamic studies of prostaglandin F-2 alpha in the utero-ovarian circulation of the sheep.
作者信息
Land R B, Baird D T, Scaramuzzi R J
出版信息
J Reprod Fertil. 1976 Jul;47(2):209-14. doi: 10.1530/jrf.0.0470209.
The concentration of prostaglandin (PG) F-2alpha in ovarian arterial blood was compared to that in aortic and carotid blood at different stages of the ovine oestrous cycle, and its concentration measured in the ovarian artery following the infusion of radioactive PGF-2alpha to the uterine vein. In all cases the concentration of PGF-2alpha increased during passage through the ovarian artery, and the increase was proportional to the log of the concentration in the uterine vein. No such change was observed in the concentration of progesterone in the ovarian artery or of PGF in the uterine artery. It was concluded that PGF-2alpha can be and is normally transferred from the uterine vein to the ovarian artery. These results are compatible with the hypothesis that PGF-2alpha of uterine origin is the normal luteolytic agent in the sheep.
在绵羊发情周期的不同阶段，比较了卵巢动脉血中前列腺素（PG）F-2α的浓度与主动脉和颈动脉血中该物质的浓度，并在向子宫静脉注入放射性PGF-2α后测定了卵巢动脉中的浓度。在所有情况下，PGF-2α在通过卵巢动脉时浓度都会升高，且这种升高与子宫静脉中浓度的对数成正比。在卵巢动脉中孕酮的浓度或子宫动脉中PGF的浓度未观察到此类变化。得出的结论是，PGF-2α能够且通常会从子宫静脉转移至卵巢动脉。这些结果与子宫来源的PGF-2α是绵羊正常黄体溶解因子这一假说相符。
Zotero 插件