Koźniewska E, Skolasińska K
Acta Physiol Pol. 1980 Jul-Aug;31(4):383-9.
The reversibility of osmotic opening of the blood-brain barrier was studied in dogs one hour after intracarotid 3 M urea injection. At that time the permeability of cerebral blood vessels to albumin is restored as evidenced by lack of Evans blue extravasation. Despite that, the response of the urea-perfused hemisphere to changes of perfusion pressure was abnormal. Blood flow in that hemisphere followed passively blood pressure changes in contrast to the contralateral hemisphere in which the blood flow remained independent of the perfusion pressure.
在经颈内动脉注射3M尿素一小时后的犬类中，研究了血脑屏障渗透开放的可逆性。那时，脑血血管对白蛋白的通透性已恢复，这可通过伊文思蓝未外渗得到证明。尽管如此，尿素灌注半球对灌注压变化的反应仍不正常。与对侧半球血流保持独立于灌注压不同，该半球的血流被动地跟随血压变化。
